Detalhe da pesquisa
1.
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.
Cell
; 177(6): 1649-1661.e9, 2019 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31080069
2.
Applications of Machine Learning to the Problem of Antimicrobial Resistance: an Emerging Model for Translational Research.
J Clin Microbiol
; 59(7): e0126020, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33536291
3.
Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality.
Proc Natl Acad Sci U S A
; 114(34): 9164-9169, 2017 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28794281
4.
CRISP(e)R drug discovery.
Nat Chem Biol
; 18(5): 435-436, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197625
5.
Antibiotic efficacy is linked to bacterial cellular respiration.
Proc Natl Acad Sci U S A
; 112(27): 8173-80, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26100898
6.
Quantification of DNA by a Thermal-Durable Biosensor Modified with Conductive Poly(3,4-ethylenedioxythiophene).
Sensors (Basel)
; 18(11)2018 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30380711
7.
Antibiotics induce redox-related physiological alterations as part of their lethality.
Proc Natl Acad Sci U S A
; 111(20): E2100-9, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24803433
8.
PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to ß-adrenergic signaling.
J Mol Cell Cardiol
; 66: 83-93, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24225179
9.
Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP.
Nat Chem Biol
; 8(4): 375-82, 2012 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22366721
10.
Computational models reduce complexity and accelerate insight into cardiac signaling networks.
Circ Res
; 108(1): 85-97, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21212391
11.
An in vitro model of the macrophage-endothelial interface to characterize CAR T-cell induced cytokine storm.
Sci Rep
; 13(1): 18835, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37914765
12.
Phospholemman is a negative feed-forward regulator of Ca2+ in ß-adrenergic signaling, accelerating ß-adrenergic inotropy.
J Mol Cell Cardiol
; 52(5): 1048-55, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22289214
13.
A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome.
Nat Commun
; 13(1): 7068, 2022 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36400796
14.
Longitudinal Analysis of Biologic Correlates of COVID-19 Resolution: Case Report.
Front Med (Lausanne)
; 9: 915367, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35783607
15.
Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure.
Front Digit Health
; 32021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34355212
16.
Growth and Stress Tolerance Comprise Independent Metabolic Strategies Critical for Staphylococcus aureus Infection.
mBio
; 12(3): e0081421, 2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34101490
17.
Clinically relevant mutations in core metabolic genes confer antibiotic resistance.
Science
; 371(6531)2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33602825
18.
Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate.
Nat Microbiol
; 4(12): 2109-2117, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31451773
19.
Antibiotic efficacy-context matters.
Curr Opin Microbiol
; 39: 73-80, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29049930
20.
Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function.
Cell Host Microbe
; 22(6): 757-765.e3, 2017 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29199098